PREDNISONE ACETATE

PREDNISONE ACETATE - Names and Identifiers

Name	Prednisone Acetate
Synonyms	Nisone U 6167 Ferrosan Delcortin Deltalone NSC 10965 Cortancyl BRN 2342061 delta-corlin PREDNISONE ACETATE Prednisone Acetate prednisone 21-acetate Prednisone 21-acetate Dehydrocortisone acetate 1-DEHYDROCORTISONE ACETATE delta1-Cortisone-21-acetate delta'-Dehydrocortisone acetate 4-08-00-03532 (Beilstein Handbook Reference) 1,4-PREGNADIEN-17,21-DIOL-3,11,20-TRIONE 21-ACETATE 17-hydroxy-3,11,20-trioxopregna-1,4-dien-21-yl acetate 1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE 21-ACETATE 1,4-Pregnadien-17-alpha,21-diol-3,11,20-trione-21-acetate Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-, 21-acetate 17 ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE-21-ACETATE Pregna-1,4-diene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy- (9CI) [2-[(17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate [2-[(8s,9s,10s,13s,14s,17r)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate
CAS	125-10-0
EINECS	204-726-0
InChI	InChI=1/C23H28O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h6,8,10,16-17,20,28H,4-5,7,9,11-12H2,1-3H3/t16?,17?,20?,21?,22?,23-/m0/s1

PREDNISONE ACETATE - Physico-chemical Properties

Molecular Formula	C23H28O6
Molar Mass	400.46
Density	1.28±0.1 g/cm3(Predicted)
Melting Point	240-242°C (dec.)
Boling Point	582.0±50.0 °C(Predicted)
Specific Rotation(α)	D25 +186° (dioxane)
Flash Point	200.2°C
Water Solubility	23mg/L(25 ºC)
Solubility	Chloroform (Slightly), Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly)
Vapor Presure	5.69E-16mmHg at 25°C
Appearance	Solid
Color	White to Off-White
pKa	12.31±0.60(Predicted)
Storage Condition	Refrigerator
Refractive Index	1.579
Physical and Chemical Properties	White or off-white crystalline powder, odorless, bitter. Insoluble in water, slightly soluble in ethanol, acetone and ethyl acetate, soluble in chloroform (1:6). Specific optical rotation [α]25D 186 ° (dioxane); Absolute ethanol solution has the maximum absorption at the wavelength of 238nm.
Use	For adrenocortical hormone drugs

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